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Assembly of extracorporeal circuit with Efferon® device and hemofilter in “POSTfilter” mode on RRT machine

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What do you need?

  • 0.9% saline solution bag, 1 liter

    0.9% saline solution bag, 1 liter

  • Plastic bag for priming solution, 2 liter

    Plastic bag for priming solution, 2 liter

  • DIN-Luer bloodlines, 2 pcs

    DIN-Luer bloodlines, 2 pcs

  • Heparin, 10 000 IU

    Heparin, 10 000 IU

  • Luer-adapter

    Luer-Luer adapter

  • Clamps, 4 pcs

    Clamps, 4 pcs

  1. Assemble the extracorporeal circuit of the RRT</strong> machine according to its user manual.*

    Step 1

  2. Add 10.000 ME heparin to saline solution and mix it to prepare the rinsing solution.

    Step 2

  3. Connect DIN-Luer bloodline 1 with priming solution bag. Fill the bloodline with the priming solution using gravity. Attach the clamp to the bloodline.

    Step 3

  4. Mount the Efferon® device in vertical position.

    Step 4

  5. Remove the cap from bottom port of the Efferon® device and connect the pre-filled DIN-Luer bloodline 1 to it.

    Step 5

  6. Remove the cap from upper port of the Efferon® device and connect the empty DIN-Luer bloodline 2 to it.

    Step 6

  7. Connect the plastic bag for rinsing solution to DIN-Luer bloodline 2.

    Step 7

  8. Remove the clamp from DIN-Luer bloodline 1 and rinse the Efferon® device using gravity.

    Step 8

  9. Put the clamps to DIN-Luer bloodlines 1 and 2 after the priming is finished.

    Step 9

  10. Disconnect the plastic bags from DIN-Luer bloodlines 1 and 2 and utilize it.

    Step 10

  11. Connect the Luer-Luer adapter to DIN-Luer bloodline 2.

    Step 11

  12. Stop the blood pump of RRT machine.

    Step 12

  13. Put the clamps on inlet and outlet bloodlines of the hemofilter.

    Step 13

  14. Disconnect the extracorporeal circuit between the hemofilter outlet and air bubble trap.

    Step 14

  15. Сonnect the bloodlinesin a sequence: DIN-Luer bloodline 1 is attached to the hemofilter, and Luer-Luer adapter is attached to the air bubble trap.

    Step 15

  16. The circuit is ready. Remove all the clamps and start the blood pump.

    Step 16
RRT POSTfilter circuit schema

* If RRT procedure is already being performed and Efferon® device should be installed in previously assembled circuit, stop the procedure, reinfuse the blood and go to recirculationmode..

** Efferon® device is symmetric, flow rate should be oriented from bottom to top.

Anticoagulation level before the start and during
the extracorporeal treatment:
— 160-210 seconds of ACT
— 60-80 seconds of aPTT

Recommended duration of use is 6-12 hours (up to 24 hours).

Instruction for Efferon®
device connection

Setup Guide for Integrating Efferon® Device into the Cardiopulmonary Bypass (CPB) Circuit

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CPB circuit schema

Assembly of extracorporeal circuit with Efferon® device and hemofilter in “PREfilter” mode on RRT machine

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RRT PREfilter circuit schema

Assembly of extracorporeal circuit with Efferon® device in isolated hemoperfusion mode on RRT machine

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RRT hemoperfusion circuit schema

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Assembly of extracorporeal circuit with Efferon® device and hemofilter in “POSTfilter” mode on RRT machine