Extracorporeal blood purification technologies

Polymeric adsorbents for selective removal of bacterial endotoxins and cytokines.

Extracorporeal treatment in sepsis and multiple organ failure.

Safe and efficient method of critical patients stabilization.

Learn more about original technology behind the Efferon^®
products.

Efferon^® LPS

Single-use therapeutic device for extracorporeal blood adsorption. Contains polymeric beads surface-modified with LPS-selective ligand.

05 November 2025

Efferon therapies are now available in Armenia!

30 October 2025

Clinical data confirmed the effectiveness of Efferon NEO in children with sepsis

18 October 2025

Efferon LPS has been approved in the Kingdom of Saudi Arabia.

Critical Care 2024, 28(Suppl 1):P220

Hemoperfusion with Efferon LPS NEO device reverts multiple organ failure, decreases IL-6 and TNF levels and systemic immune inflammation in children with sepsis

Shock. 2023 Jun 1;59(6):846-854

Hemoperfusion using the LPS-selective mesoporous polymeric adsorbent in septic shock: a multicenter randomized clinical trial

Intensive Care Medicine Experimental 2022, 10(2): 000710

Extracorporeal hemoperfusion with Efferon LPS for rapid reconstitution of vital parameters and decreasing proinflammatory biomarkers in patients with intra-abdominal sepsis

World Journal of Medical Case Reports. Vol. 2, No. 3, 2021, pp. 46-50.

Application of novel device Efferon LPS in hemoperfusion for simultaneous removal of endotoxin and cytokines in a patient with septic shock

Therapeutic archive. 2021; 93 (7): 811-817

Extracorporeal adsorption of cytokines in cytokine release syndrome in a patient with acute lymphoblastic leukemia after therapy with T cells with a chimeric antigen receptor. Clinical observation

General resuscitation. 2020; 16 (6): 31-53.

Application of adsorbent based on a hypercrosslinked styrene-divinylbenzene copolymer with an immobilized LPS-selective ligand in hemoperfusion for the treatment of patients with septic shock

General resuscitation. 2020; 16 (4): 14-20.

Hemosorption carried out by a column filled with hypercrosslinked styrene-divinibenzene copolymer with an immobilized LPS-selective ligand in a complex of intensive treatment of acute lung injury in the surgical treatment of lung cancer (clinical observation)

General resuscitation. 2018; 14 (6): 51-60.

Efficiency and safety of a new product for LPS-selective hemosorption (experimental study)

General resuscitation. 2016; 12 (6): 82-107.

Sorbents for extracorporeal removal of toxic substances and molecules with unwanted biological activity (review)

General resuscitation. 2017; 13 (5): 109-120.

Methods for the determination of bacterial endotoxin in critical care medicine (review).