Assembly of extracorporeal circuit with Efferon® device and hemofilter in “PREfilter” mode on MultiFiltrate RRT machine or its analogues

0,9% saline solution bag, 1 liter

Plastic bag for priming solution, 2 liter

DIN-Luer bloodline,
2 pcs

Heparin,
10.000 ME

DIN-DIN
bloodline

Clamps,
4 pcs
Assemble the extracorporeal
circuit of the RRT machine
according to its user manual.

Add 10.000 ME heparin
to saline solution and mix
it to prepare the rinsing
solution.

Connect DIN-Luer bloodline 1
with priming solution bag.
Fill the bloodline with the priming
solution using gravity. Attach
the clamp to the bllodline

Mount the Efferon® device
in vertical position.**

Remove the cap from bottom port of
the Efferon® device and connect the
pre-filled DIN-Luer bloodline 1 to it.

Remove the cap from upper
port of the Efferon® device and
connect the empty DIN-Luer
bloodline 2 to it.

Connect the plastic bag for
rinsing solution to DIN-Luer
bloodline 2.

Remove the clamp from
DIN-Luer bloodline 1 and
rinse the Efferon® device
using gravity.

Put the clamp on DIN-Luer
bloodline 1 after the priming
is finished.

Disconnect DIN-Luer
bloodline 2 from the
upper port of the Efferon®
device and attach
DIN-DIN bloodline to it

Remove the clamp from
the DIN-Luer bloodline 1.
Fill the DIN-DIN bloodline
with priming solution, then
attach the clamps to both
bloodlines

Stop the blood pump
of RRT machine

Put the clamps on inlet
and outlet bloodlines
of the hemofilter

Disconnect the DIN-Luer
bloodline 1 from bottom port
of the Efferon® device. Take
care of air bubbles not
to enter inside.

Disconnect the “red”
bloodline at the inlet
of the hemofilter

And connect it to lower
port of the Efferon® device

Connect the DIN-DIN
bloodline and inlet port
of hemofilter.

The circuit is ready.
Remove all the clamps
and start the blood pump.

the extracorporeal treatment:
— 160-210 seconds of ACT
— 60-80 seconds of aPTT
(up to 12 hours)
device connection